![]() ![]() However, our mechanistic understanding of how these environments regulate host-pathogen interactions in humans is poorly understood. Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. 9Biodesign Center for Immunotherapy, Vaccines and Virotherapy, Arizona State University, Tempe, AZ, United States.8School of Mechanical Engineering, Weldon School of Biomedical Engineering and Department of Basic Medical Sciences, Purdue University, West Lafayette, IN, United States.7Department of Animal Care & Technologies, Arizona State University, Tempe, AZ, United States.6Biomedical Research and Environmental Sciences Division, NASA Johnson Space Center, Houston, TX, United States.5Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States.4Bioinformatics Core Facility, Bioscience, Knowledge Enterprise, Arizona State University, Tempe, AZ, United States.Department of Agriculture, Gainesville, FL, United States 3Genomics and Bioinformatics Research Unit, Agricultural Research Service, U.S.2School of Life Sciences, Arizona State University, Tempe, AZ, United States.1Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.Nauman 8, Wei Kong 9, Jason Steel 4 and Cheryl A. ![]() Mark Ott 6, Sandhya Gangaraju 1, Bianca Y. Franco Meléndez 1,2,3, Shanshan Yang 4, Kristina Buss 4, Trenton J. Jennifer Barrila 1*, Jiseon Yang 1, Karla P. ![]()
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